厦门大学平台管理系统 Lab for Computational Medicine and Bioinformatics--Home--Paper Publications

Guiling Guo,Zhenyu Shao,Heying Luo,Ziqing Fu,Hui Xiong,Jin Li,Qingqing Qin,Xiaoqing Yang,Shuxiang Hu,Jinzhun Wu.KGRD: a knowledge-graph-augmented automated reasoning framework for diagnosis and counselling of paediatric rare genetic disorders.npj Digital Medicine,2026,
Lu Chen,Jintao Guo,Fei Li,Mingjie Gao,Daxuan Wang,Yali Zheng,Xiaoting Hong,Wenqing Zhang,Runyang Li,Zhaozhang Huang,Yaolin Zhen,Chunyi Gao,Jihuan Hou,Qiang Yu,Bowen Zheng,Xuemei Chen.FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3-Mediated ErbB3 Fucosylation in Lung Adenocarcinoma.Advanced Science,2026,
Ya Luo,Jun Ren,Qian Yang,Zhiyu You,Ying Zhou,Qingqing Qin.Benchmarking RNA velocity methods across 17 independent studies.Cell Reports Methods,2026,
Hongkun Fang,Hao Wang,Xinyue Liu,Wencheng Zhao,Yujin Liu,Li Ye,Kandi Xu,Lishu Zhao,Yi Deng.HMOX1 expression influence the role of macrophage in EGFR-TKI resistance of lung adenocarcinoma.International Immunopharmacology,2025,
Jing Yang,Lingtao Yang,Ying Zhou,Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility.Journal of Translational Medicine,2025,23(792):
Dandan Hu,Jialin Zhao,Miaoqing Wu,Ying Zhou,Beile Lyu,Weiwei Tang,Jintao Guo,Hui Zhang,Zixuan Su,Chao Huang,Chaoqun Xu.Microbial interactions induce the mutational signature of mismatch repair deficiency in colorectal cancer and associated with EPPK1 mutations.Cancer Letters,2025,625
Yuanyuan Zeng,Longbiao Chen,Xiaowen Lyu,Jialiang Huang,Ying Zhou,Jialin Zhao,Jiayang Guo,Zhiyu You.Chrombus-XMBD: a graph convolution model predicting 3D-genome from chromatin features.Briefings in Bioinformatics,2025,26(3):
Jun Ren,Xiaodong Shi,Jintao Guo,Xuejing Lyu,Hongkun Fang,Jing Yang,Yudi Hu,Ying Zhou.MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination.[J].elife,2025,13
Shuai Wang,Ting He,Ya Luo,SOX4 facilitates brown fat development and maintenance through EBF2-mediated thermogenic gene program in mice.[J].Cell Death & Differentiation,2024,32(3):447-465.
Jintao Guo,Qiwei Guo,Hongkun Fang,Xin Jin,Ailing Hour,Huanhuan Zhu,Xin Wu,You Yang,Dandan Jin,Jieqiong Xie,Taoling Zhong,Ying Zhou,Qinwei Chen,Zhongmin Xia,Chaoqun Xu.Phenome-wide association study in 25,639 pregnant Chinese women reveals loci associated with maternal comorbidities and child health.[J].Cell Genomics,2024,4(10):

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